ea0065oc6.3 | Reproductive Endocrinology and Biology | SFEBES2019
Timms Kate
, Cartland Sarah J
, Ntostis Panagiotis
, Saravanan Ponnusamy
, Simpson Nigel
, Scott Eleanor
, Forbes Karen
Gestational diabetes mellitus (GDM) increases fetal morbidity/mortality, and is associated with elevated risks of offspring cardiometabolic disease. These risks are compounded in infants born large for gestational age (LGA) rather than appropriate size (AGA), a common complication of GDM associated with altered placental function. Circulating extracellular vesicle (EV)-associated miRNAs are internalised into the placenta and are emerging as key GDM mediators, with their role i...